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The Complete Guide to the O-Shot® Procedure: Finding the Right Provider in Greenville, NC

Understanding the O-Shot Procedure: A Revolutionary Approach to Women’s Sexual Wellness

The O-Shot, short for Orgasm Shot, represents a breakthrough in women’s sexual health and wellness. This innovative procedure harnesses the power of your body’s own healing mechanisms through Platelet-Rich Plasma (PRP) therapy to address a range of intimate concerns that many women experience but few feel comfortable discussing.

Developed by Dr. Charles Runels, a pioneer in regenerative medicine, the O-Shot Procedure uses PRP derived from your own blood to rejuvenate vaginal and clitoral tissue. The procedure involves drawing a small amount of your blood, processing it to concentrate the platelets and growth factors, and then strategically injecting this enriched plasma into specific areas to enhance sensation, function, and overall sexual wellness.

At Biltmore Restorative Medicine & Aesthetics, we’ve witnessed firsthand how this treatment can transform lives. Our approach goes beyond simply performing a procedure—we look at each patient as a whole person, understanding that sexual wellness is intricately connected to overall health, hormonal balance, and quality of life.

What Does the O-Shot Treat?

Women come to us seeking help with a variety of concerns, many of which they’ve struggled with silently for years. The O-Shot has proven effective for addressing multiple conditions:

Sexual Dysfunction and Desire Issues: Many women experience diminished sexual desire or arousal at various points in their lives. Whether due to hormonal changes, stress, or other factors, this loss of libido can affect relationships and self-confidence. The O-Shot works to enhance blood flow and sensitivity in intimate areas, often reigniting the spark that seemed lost.

Difficulty Achieving Orgasm: Anorgasmia, or the inability to achieve orgasm, affects countless women. Some have never experienced orgasm, while others have lost this ability over time. By rejuvenating nerve endings and increasing blood flow to the clitoris and anterior vaginal wall, the O-Shot can restore or enhance orgasmic function.

Loss of Sensation and Sensitivity: As we age, or following childbirth, many women notice decreased sensation during intimacy. The vaginal tissue may feel less responsive, and pleasure that once came easily now seems elusive. The regenerative properties of PRP can restore sensitivity by promoting tissue renewal and nerve regeneration.

Urinary Incontinence: Stress urinary incontinence—the involuntary leakage of urine during physical activity, coughing, sneezing, or laughing—affects millions of women, particularly after childbirth or during menopause. The O-Shot strengthens the tissues around the urethra, providing support that can significantly reduce or eliminate these embarrassing episodes.

Vaginal Dryness: This common concern, especially prevalent during perimenopause and menopause, can make intercourse uncomfortable or even painful. The O-Shot stimulates natural lubrication and improves tissue health, making intimacy pleasurable again.

Painful Intercourse (Dyspareunia): Pain during sex can stem from various causes, including tissue thinning, scarring, or decreased lubrication. By promoting tissue regeneration and improving elasticity, the O-Shot often provides relief where other treatments have failed.

Postpartum Changes: Childbirth, while miraculous, can leave lasting effects on vaginal tissue, pelvic floor strength, and sexual function. Many new mothers find that their bodies don’t feel quite the same afterward. The O-Shot offers a path to reclaiming your pre-pregnancy sensation and function.

Age-Related Sexual Concerns: The natural aging process affects every aspect of our bodies, including intimate tissues. Decreased estrogen production leads to tissue thinning, reduced elasticity, and diminished sensation. The O-Shot provides a non-hormonal option for addressing these changes.

Lichen Sclerosus Symptoms: This chronic inflammatory condition affects the vulvar skin, causing itching, discomfort, and changes in tissue structure. While the O-Shot is not a cure, many patients experience significant symptom relief and improved tissue quality.

How Does the O-Shot Work? The Science Behind Regeneration

Understanding the science behind the O-Shot helps explain why this treatment can be so transformative. At its core, the procedure leverages your body’s innate healing capabilities.

The Power of Platelet-Rich Plasma

Your blood contains platelets, which are primarily known for their role in clotting. However, platelets also contain numerous growth factors—proteins that signal tissue to heal and regenerate. When we concentrate these platelets through centrifugation, we create a powerful therapeutic substance rich in growth factors including platelet-derived growth factor (PDGF), transforming growth factor (TGF), vascular endothelial growth factor (VEGF), and epidermal growth factor (EGF).

Stimulating Natural Regeneration

When this concentrated PRP is injected into specific areas of the vaginal and clitoral tissue, it initiates a cascade of healing responses. The growth factors stimulate the production of new collagen and elastin—the structural proteins that give tissue its strength and elasticity. They also promote angiogenesis, the formation of new blood vessels, which enhances blood flow to the treated areas.

Enhanced Nerve Function

The growth factors in PRP don’t just work on tissue structure—they also support nerve health and function. Improved nerve density and sensitivity translate directly to enhanced sensation and pleasure.

Tissue Rejuvenation

Over time, the regenerated tissue becomes healthier, more elastic, and more responsive. The anterior vaginal wall (the G-spot area) may become more prominent and sensitive. The clitoral tissue experiences enhanced blood flow and sensitivity. The urethral support strengthens, often resolving incontinence issues.

This regenerative process continues for weeks and even months after the injection, with most patients experiencing progressive improvements rather than immediate results. This gradual enhancement reflects true tissue healing rather than temporary effects from fillers or other substances.

The O-Shot Procedure: What to Expect at Biltmore Restorative Medicine

We understand that considering any intimate procedure can feel vulnerable. At Biltmore Restorative Medicine & Aesthetics, we’ve created an environment where you can feel completely comfortable discussing your concerns and receiving treatment with the utmost privacy and respect.

Your Initial Consultation

Every patient journey begins with a comprehensive consultation. This is your opportunity to discuss your specific concerns, health history, and goals in a private, judgment-free environment. We take time to understand not just your symptoms, but how they’re affecting your life and relationships. During this consultation, we’ll evaluate whether you’re a good candidate for the O-Shot, discuss what you can realistically expect, and answer all your questions.

The Day of Your Procedure

When you arrive for your O-Shot treatment, you can expect the entire process to take approximately 45 minutes to an hour. We begin by applying a topical numbing cream to ensure your comfort throughout the procedure. This cream typically needs 20-30 minutes to take full effect, during which time you can relax in our comfortable treatment room.

Blood Collection and PRP Preparation

While the numbing cream works, we draw a small amount of blood—similar to a routine blood test. This blood is immediately processed using our state-of-the-art centrifuge system, which spins the blood at carefully calibrated speeds to separate and concentrate the platelets. At Biltmore Restorative Medicine, we use advanced PRP processing techniques to ensure the highest concentration and quality of platelets—a critical factor that distinguishes exceptional results from mediocre ones.

The concentration of your PRP matters significantly. Not all PRP is created equal, and this is one area where you should never compromise on quality. We’re transparent about our process and happy to discuss the specific platelet concentrations we achieve, typically ranging from 4 to 8 times the baseline platelet count found in whole blood.

The Injection Process

Once the area is completely numb and your PRP is prepared, we perform the actual injections. Using precise technique, we inject the PRP into specific areas: the anterior vaginal wall (including the area commonly called the G-spot), around the clitoris, and sometimes near the urethra for patients concerned with incontinence. The entire injection process takes only a few minutes.

Most patients report feeling minimal to no discomfort during the injections thanks to the numbing cream. You might feel slight pressure or a brief sensation, but pain is rare when the procedure is performed correctly with adequate numbing.

Immediate Post-Procedure Care

After the injections, you can return to most normal activities immediately. We typically recommend avoiding sexual activity for 3-4 days to allow the treatment area to heal optimally. Some patients prefer to take the rest of the day to relax, while others return directly to work or daily activities.

Benefits of the O-Shot: Beyond Expectations

The transformative potential of the O-Shot extends across multiple dimensions of sexual health and overall wellness. Patients consistently report improvements that go far beyond what they initially hoped to achieve.

Enhanced Sexual Arousal and Sensitivity

Perhaps the most commonly reported benefit is a heightened level of sexual arousal and sensitivity. Women describe sensations becoming more intense, more pleasurable, and more easily accessed. The physical changes in tissue sensitivity translate to a renewed interest in intimacy and greater ease in becoming aroused.

Improved Natural Lubrication

Many patients notice a significant increase in natural lubrication, often within the first few weeks after treatment. This occurs as the regenerated tissue begins producing more moisture naturally, eliminating the need for artificial lubricants and making intimacy more spontaneous and comfortable.

Stronger and More Frequent Orgasms

This benefit often surprises patients with its profound impact. Women report that orgasms become not just more achievable, but stronger, longer-lasting, and sometimes multiple. For women who have never experienced orgasm, the O-Shot can open an entirely new dimension of pleasure.

Reduced Urinary Incontinence

The strengthening effect on tissues surrounding the urethra frequently provides dramatic relief from stress urinary incontinence. Many women find they can laugh, sneeze, exercise, and engage in activities without fear of embarrassing leakage—a life-changing improvement in quality of life.

Enhanced Tissue Quality and Appearance

The vulvar and vaginal tissues often take on a more youthful, healthy appearance. The skin becomes smoother, more elastic, and better hydrated. While this isn’t typically a primary concern for most patients, many appreciate this aesthetic improvement.

Non-Surgical, Minimally Invasive Solution

Unlike surgical interventions, the O-Shot requires no incisions, no anesthesia beyond topical numbing cream, and involves minimal risk and downtime. You’re using your own body’s healing factors, not foreign substances.

Natural-Looking and Natural-Feeling Results

Because the improvements come from your body’s own regenerative processes, results feel completely natural. There are no implants, no foreign materials, and no artificial substances—just your own enhanced tissue.

Quick Recovery and Minimal Downtime

Most patients resume normal activities immediately, with only a brief restriction on sexual activity. There’s no lengthy recovery period, no surgical wounds to heal, and no significant disruption to your life.

Who is a Good Candidate for the O-Shot?

The O-Shot can benefit a wide range of women, but it’s essential to understand whether this treatment aligns with your specific situation and goals.

Ideal Candidates Include:

Women experiencing any form of sexual dysfunction, whether difficulty with arousal, achieving orgasm, or maintaining interest in intimacy. These concerns may have been present throughout your life or developed more recently.

Those dealing with stress urinary incontinence or urge incontinence. If you find yourself planning your activities around bathroom locations or wearing protective pads “just in case,” the O-Shot may offer significant relief.

Postpartum women seeking restoration of their pre-pregnancy sexual function. Childbirth is miraculous, but it can leave lasting changes. We typically recommend waiting at least 6-8 weeks after delivery, and preferably until you’ve finished breastfeeding, though we evaluate each situation individually.

Perimenopausal and postmenopausal women experiencing the effects of declining estrogen on vaginal tissue, lubrication, and sexual function. The O-Shot offers a non-hormonal option that can work beautifully alongside or independently of hormone optimization therapy.

Women with vaginal dryness making intercourse uncomfortable or painful. This symptom can occur at any age due to various factors including hormonal changes, medications, stress, or health conditions.

Those seeking natural, non-hormonal options for sexual wellness. While we’re strong advocates for appropriate hormone optimization, we recognize that not everyone is a candidate for or interested in hormone therapy. The O-Shot provides an effective alternative.

General Health Considerations

Good candidates are generally in good overall health, don’t have active infections, and have realistic expectations about what the procedure can achieve. The O-Shot can produce remarkable results, but it’s not magic—individual responses vary based on numerous factors.

Who Should NOT Get the O-Shot:

Certain situations make the O-Shot inadvisable, at least temporarily:

  • Women who are pregnant or actively trying to conceive
  • Those with active infections in the treatment area
  • Patients with certain blood disorders or those taking blood thinners (though we can often work with your physician to manage this)
  • Anyone with unrealistic expectations about instant or guaranteed results
  • Those with active cancer or undergoing cancer treatment (we evaluate these situations carefully and individually)

During your consultation at Biltmore Restorative Medicine, we conduct a thorough evaluation to determine whether the O-Shot is appropriate for your unique situation. If it’s not the right fit, we’ll discuss alternative approaches that might better serve your needs.

Finding the Best O-Shot Provider in Greenville: What You Need to Know

The quality of your results depends significantly on the expertise and approach of your provider. Not all O-Shot procedures are performed equally, and choosing the right practitioner is perhaps the most important decision you’ll make.

Essential Questions to Ask Potential Providers

Experience and Volume

Don’t hesitate to ask, “How many O-Shot procedures have you performed?” Experience matters tremendously with any medical procedure, but particularly with techniques requiring precision and finesse. A provider who has performed dozens or hundreds of procedures will have refined their technique, learned to handle variations, and developed the judgment that comes only with experience.

Follow up with questions about how long they’ve been offering the treatment and what kind of success rates they’re seeing with patients. Be wary of providers who are vague about their experience or seem to have just added this service to their menu.

Training and Certification

Ask directly: “Are you certified by Dr. Charles Runels and the Cellular Medicine Association?” This certification indicates that the provider has received proper training in the specific technique developed by Dr. Runels. However, certification alone isn’t enough—ask about ongoing education and whether the provider stays current with advances in PRP therapy.

At Biltmore Restorative Medicine, our commitment to exceptional training goes beyond basic certification. I’ve dedicated myself to becoming one of the most highly trained physicians in hormone optimization and regenerative medicine, and I bring that same commitment to excellence to every procedure we offer.

PRP Quality and Concentration

This is where many providers differ significantly, and it directly affects your results. Ask these specific questions:

  • “What PRP system do you use?”
  • “What platelet concentration do you typically achieve?”
  • “How do you ensure consistent PRP quality?”
  • “Do you use FDA-cleared centrifuge systems?”

The concentration of platelets in your PRP can vary enormously between clinics—some achieve only 2-3 times baseline concentration, while others consistently reach 6-8 times or higher. This difference matters. Higher concentrations generally produce more dramatic results, though the relationship isn’t perfectly linear. Quality also depends on processing technique, timing, and the specific protocols used.

We’re completely transparent about our PRP process and the concentrations we achieve. If a provider seems reluctant to discuss these details or brushes off your questions about PRP quality, that’s a significant red flag.

Consultation and Personalization

Ask whether you can schedule a private consultation before committing to treatment. Any reputable provider will not only allow this but insist upon it. During this consultation, assess whether the provider:

  • Listens carefully to your specific concerns
  • Asks detailed questions about your medical history
  • Discusses your goals and expectations thoroughly
  • Explains the procedure clearly
  • Addresses risks and potential side effects honestly
  • Makes you feel comfortable discussing intimate topics

Our approach at Biltmore Restorative Medicine looks at the patient as a whole. Sexual wellness doesn’t exist in isolation—it’s connected to hormonal balance, overall health, stress levels, relationships, and numerous other factors. We take time to understand your complete health picture, not just the symptoms you’re seeking to address.

Follow-up and Results Tracking

Find out what kind of follow-up care the provider offers. Will they check in with you after treatment? Do they track outcomes? What happens if you don’t achieve the results you hoped for?

Quality providers stand behind their work and remain engaged with your progress. They want to know how you’re responding, whether adjustments might help, and how they can support your ongoing wellness journey.

Key Credentials to Verify

Beyond asking questions, verify certain credentials independently:

Board Certification: Your provider should be board-certified in a relevant specialty—obstetrics and gynecology, family medicine, urology, or another field that provides appropriate medical background. Board certification indicates a physician has completed rigorous training and maintains current knowledge in their field.

Medical License: Verify that your provider holds an active, unrestricted medical license in North Carolina. This information is publicly available through the North Carolina Medical Board website.

Cellular Medicine Association Certification: While you can ask the provider about this, the Cellular Medicine Association also maintains information about certified providers.

Facility Standards: Consider where the procedure will be performed. While the O-Shot doesn’t require a surgical center, the facility should maintain high standards of cleanliness, use sterile technique, and have appropriate equipment.

Malpractice Insurance: Any legitimate medical provider carries appropriate malpractice insurance. While you may not need to verify this explicitly, it’s part of the foundation of professional medical practice.

Red Flags to Watch For

Trust your instincts if something doesn’t feel right. Specific warning signs include:

Reluctance to Answer Questions: Providers who seem defensive, dismissive, or evasive when you ask about their training, experience, or techniques should raise concerns. Medical care is a partnership, and you have every right to thoroughly vet anyone who will be treating you.

Guaranteed Results or Unrealistic Promises: No legitimate medical provider can guarantee specific results from the O-Shot. While success rates are high and most patients experience significant benefits, individual responses vary. Providers who promise you’ll achieve specific outcomes or describe the treatment as a miracle cure lack either honesty or understanding.

Pressure Tactics: High-pressure sales tactics have no place in medicine. If a provider pushes you to book immediately, offers “limited-time” discounts that expire today, or makes you feel rushed in your decision, walk away. Quality medical care involves thoughtful consideration, not impulse decisions.

Unwillingness to Discuss Risks: Every medical procedure carries some risk, even minimally invasive ones like the O-Shot. Providers who skip over potential side effects or dismiss your concerns about risks are not providing informed consent.

No Consultation Process: If a provider is willing to perform the procedure without a thorough consultation and evaluation, that’s a major red flag. Cookie-cutter medicine doesn’t serve patients well, especially for something as personal and individual as sexual wellness.

Prices Significantly Below Market: While cost matters, extremely low prices often indicate corners being cut somewhere—perhaps in PRP quality, technique, sterility protocols, or provider experience. The old adage “you get what you pay for” often applies in medicine.

No Follow-up Care: Providers who view the O-Shot as a one-and-done transaction rather than part of an ongoing wellness journey are missing a crucial element of quality care.

Critical Factors to Consider Before Getting the O-Shot

Understanding the Financial Investment

The O-Shot is considered an elective procedure, meaning health insurance typically doesn’t provide coverage. This places the financial responsibility on you, so it’s important to understand the costs involved and what you’re paying for.

Average Cost in Greenville

In the Greenville area, you can expect O-Shot pricing to range from approximately $1,200 to $2,500 per session. This variation reflects differences in provider experience, PRP quality and concentration, facility standards, and the comprehensiveness of care provided.

At Biltmore Restorative Medicine, our pricing reflects our commitment to using the highest quality PRP processing systems, maintaining rigorous quality standards, and providing the level of expertise and personalized care that produces exceptional results. When evaluating cost, consider what you’re receiving for your investment.

What’s Included

Ask specifically what the quoted price includes. At a minimum, it should encompass:

  • Initial consultation
  • The blood draw
  • PRP processing
  • The injection procedure itself
  • Topical numbing cream
  • Follow-up consultation to assess results

Some clinics quote a base price but add fees for consultation, numbing agents, or follow-up care. We believe in transparent pricing with no surprise charges.

Multi-Session Packages

While many patients achieve excellent results with a single treatment, some benefit from a series. We typically recommend trying a single session first and assessing your response before committing to multiple treatments. However, some clinics offer package pricing if you choose to schedule multiple sessions upfront.

Financing Options

We understand that even elective procedures represent a significant investment. Ask about financing options if the upfront cost is prohibitive. Many practices partner with medical financing companies that offer payment plans.

HSA and FSA Accounts

While insurance doesn’t cover the O-Shot, you may be able to use Health Savings Account (HSA) or Flexible Spending Account (FSA) funds for the procedure. Check with your account administrator, as policies vary.

Value Beyond Price

When evaluating cost, consider the value of improved sexual function, restored confidence, relief from incontinence, and enhanced quality of life. For many patients, the O-Shot proves to be one of the most valuable investments they’ve made in their health and wellbeing.

Risks and Side Effects: What You Should Know

While the O-Shot is considered very safe because it uses your own blood-derived PRP, no medical procedure is entirely without risk. Understanding potential side effects allows you to make an informed decision and recognize normal versus concerning symptoms.

Common, Expected Side Effects:

Temporary swelling at the injection sites is completely normal and typically resolves within 24-48 hours. You might notice slight puffiness or fullness in the treated areas. This actually indicates that the PRP is working—the initial inflammatory response is part of the healing cascade.

Bruising can occur, though it’s usually mild. Because we’re working with vascular tissue and you’ve had injections, some bruising is possible even with expert technique. This typically fades within a few days to a week.

Mild discomfort or tenderness at the injection sites may persist for a day or two after the numbing wears off. Most patients describe this as minor and easily managed with over-the-counter pain relievers if needed.

Temporary increased sensitivity in the treated areas is common and is actually a positive sign. Some patients notice heightened sensation even before the full effects develop.

Slight spotting or discharge is possible in the first day or two. This is generally minimal and resolves quickly.

Rare Complications:

Infection is extremely rare when proper sterile technique is used. At Biltmore Restorative Medicine, we maintain rigorous sterility protocols. However, with any procedure involving injection through the skin, infection is a theoretical risk. Signs of infection—increasing pain, redness, warmth, fever, or unusual discharge—should be reported immediately.

Allergic reactions to the numbing cream can occur in rare cases. We use high-quality, pharmaceutical-grade numbing agents, and allergic reactions are uncommon. However, if you have known allergies to local anesthetics, inform us during your consultation.

Scarring or tissue damage is exceptionally rare with proper technique but remains a theoretical possibility any time we work with tissue.

The “Non-Responder” Phenomenon

Perhaps the most frustrating outcome isn’t a complication but rather no improvement. While most patients respond very positively to the O-Shot, some don’t experience the degree of improvement they hoped for. Factors affecting response include:

  • The severity and nature of your initial concerns
  • Your overall health and healing capacity
  • Hormonal status (particularly estrogen levels)
  • Age and tissue quality before treatment
  • The quality and concentration of the PRP used
  • Individual biological variability

If you don’t respond optimally to the first treatment, we explore why. Sometimes addressing underlying hormonal imbalances or other health factors improves response to a subsequent treatment. Other times, combining the O-Shot with complementary therapies produces better results.

Our Commitment to Safety

At Biltmore Restorative Medicine, we prioritize your safety above all else. We use sterile technique, FDA-cleared equipment, and maintain protocols that minimize risk. During your consultation, we review your complete medical history to identify any factors that might increase your risk or affect your response to treatment.

Individual Results and Setting Realistic Expectations

One of the most important conversations we have during consultations involves expectations. The O-Shot can produce remarkable, life-changing results—I’ve seen it transform patients’ lives countless times. However, individual responses vary, and multiple factors influence outcomes.

Factors Affecting Your Results:

Age and Hormonal Status: Younger women with adequate estrogen levels often respond very robustly to PRP therapy. Their tissues have excellent regenerative capacity and respond eagerly to growth factor stimulation. Postmenopausal women can also achieve excellent results, though the response sometimes develops more gradually and may benefit from concurrent hormone optimization.

In my practice, I’ve found that addressing hormonal balance—particularly estrogen, testosterone, and thyroid hormones—often enhances response to regenerative treatments like the O-Shot. When hormone levels are optimized, tissues have the building blocks they need to respond fully to growth factor stimulation.

Overall Health Status: Your general health matters. Women who maintain good nutrition, regular exercise, healthy body weight, and don’t smoke typically heal better and respond more robustly to regenerative treatments. Certain conditions—uncontrolled diabetes, autoimmune disorders, significant vascular disease—can affect healing and may diminish response.

Severity of Initial Concerns: Sometimes expectations need adjustment based on the severity of your starting point. Mild to moderate sexual dysfunction often responds more dramatically than severe, long-standing issues. This doesn’t mean severe cases can’t improve—many do significantly—but the degree of improvement may differ.

Tissue Quality: If you’ve experienced significant tissue changes from aging, hormonal deficiency, or other factors, restoration may be more gradual. Think of it like renovating a house—if the foundation needs work, improvements take longer than simple cosmetic updates.

Lifestyle Factors: Smoking significantly impairs healing and tissue regeneration. Chronic stress affects hormone levels and healing capacity. Poor nutrition deprives your body of the building blocks needed for tissue repair. These lifestyle factors can significantly impact your results.

PRP Quality: As discussed extensively, the quality and concentration of the PRP used profoundly affects outcomes. This is one factor completely within our control, which is why we’re so committed to using optimal processing techniques.

Realistic Timeline

Understanding the timeline for improvement helps set appropriate expectations. Unlike filler injections that provide immediate (though temporary) volume, the O-Shot works through tissue regeneration—a process that takes time.

Most patients begin noticing improvements within 3-6 weeks after treatment. However, the full effects continue developing for 2-4 months as new collagen forms, new blood vessels develop, and tissue remodeling continues. Some patients report that results keep improving even beyond this timeframe.

What Success Looks Like

Success doesn’t necessarily mean every symptom resolves completely, though that certainly happens for many patients. More often, success means significant improvement in symptoms and quality of life:

  • Sexual desire increases, though maybe not to teenage levels
  • Orgasms become achievable or more intense
  • Urinary incontinence improves dramatically or resolves
  • Vaginal dryness decreases significantly
  • Painful intercourse becomes comfortable
  • Overall sexual satisfaction improves markedly

The goal is meaningful improvement that enhances your quality of life, not necessarily perfection. During your consultation, we’ll discuss what realistic outcomes look like for your specific situation.

The Importance of Specialized, Comprehensive Care

Why Choose a Regenerative Medicine Specialist

Sexual wellness doesn’t exist in isolation—it’s intimately connected to hormone balance, overall health, stress levels, relationship dynamics, and numerous other factors. This is why comprehensive, specialized care often produces superior outcomes compared to procedures performed in isolation.

The Whole-Person Approach

At Biltmore Restorative Medicine & Aesthetics, our approach looks at the patient as a whole. When you come to us with concerns about sexual function, we don’t just address the immediate symptom—we explore the underlying factors contributing to your experience.

Is hormonal imbalance playing a role? Many women suffering from sexual dysfunction, low libido, or vaginal dryness are experiencing the effects of hormonal deficiency or imbalance. Addressing these hormonal issues—whether through bioidentical hormone replacement therapy, thyroid optimization, or other approaches—can dramatically enhance response to treatments like the O-Shot.

Could stress or cortisol dysregulation be involved? Chronic stress affects virtually every body system, including sexual function. High cortisol can suppress other hormones and affect blood flow, sensation, and desire.

Are nutritional deficiencies limiting your healing capacity? Optimal tissue regeneration requires adequate protein, vitamins, minerals, and other nutrients. We sometimes identify and address deficiencies that were hampering healing.

Is pelvic floor dysfunction contributing? Some patients benefit from concurrent pelvic floor physical therapy, which can complement the O-Shot beautifully.

This comprehensive approach means we’re not just treating symptoms—we’re addressing root causes and optimizing your body’s capacity to heal and function optimally.

Depth of Expertise in Sexual Wellness

Providers who focus specifically on sexual wellness and regenerative medicine develop a depth of understanding that general practitioners simply can’t match. We see patterns, understand nuances, and can draw on extensive experience with similar cases to optimize your treatment plan.

Moreover, comfort discussing intimate topics comes more naturally when it’s your area of focus. We create an environment where you can discuss sensitive concerns without embarrassment, knowing you’re talking with someone who handles these conversations regularly and approaches them with professionalism and compassion.

Access to Multiple Treatment Modalities

Specialized clinics typically offer multiple approaches to sexual wellness, allowing for customized treatment plans. At Biltmore Restorative Medicine, we can combine the O-Shot with:

  • Bioidentical hormone replacement therapy
  • Other regenerative treatments
  • Aesthetic treatments that enhance confidence
  • Nutritional optimization
  • Stress management strategies

This flexibility allows us to create truly personalized treatment plans rather than offering a one-size-fits-all approach.

Commitment to Advanced Technology

Specialized practices invest in the best equipment and stay current with advances in their field. We use state-of-the-art PRP processing systems, maintain rigorous quality standards, and continually educate ourselves about new developments in regenerative medicine.

The Biltmore Restorative Medicine Difference

When I opened Biltmore Restorative Medicine & Aesthetics in Greenville in 2013, my goal was clear: to provide the most exceptional care in hormone optimization, anti-aging, and regenerative medicine—services equivalent only to those offered in larger metropolitan areas. I wanted patients in Western North Carolina to access premium care without traveling to Charlotte, Atlanta, or beyond.

Exceptional Training and Experience

My journey to founding this practice has been driven by a deep commitment to helping others feel like themselves again. After my diagnosis with multiple sclerosis ten years ago, I became intimately familiar with the challenges of managing chronic conditions and the profound impact that optimal medical care can make. This personal experience reinforced my dedication to providing exceptional care to every patient.

My goal has always been to be the most highly trained, experienced physician practicing hormone optimization and regenerative medicine. I’ve pursued extensive training beyond my medical degree and board certification, becoming certified in procedures like the O-Shot through Dr. Runels’ Cellular Medicine Association and continually expanding my expertise in regenerative therapies.

Comprehensive Hormone Optimization

One of our specialties at Biltmore Restorative Medicine is hormone optimization for both women and men. I’ve spent years studying hormone therapy, speaking on topics like the dangers of untreated menopause and andropause, and helping countless patients understand that hormone optimization is the most natural and safest way to lower risks of cardiac disease, Alzheimer’s, osteoporosis, and many other ailments.

This expertise in hormone optimization directly enhances outcomes from treatments like the O-Shot. When hormones are balanced, tissues are healthier, healing is optimized, and sexual function improves. Many patients find that combining hormone optimization with the O-Shot produces results that exceed what either treatment could achieve alone.

Quality Without Compromise

We never compromise on quality. From our PRP processing systems to our sterile technique to the time we spend with each patient, everything reflects our commitment to excellence. The concentration of PRP we achieve, the precision of our technique, and the comprehensiveness of our approach all contribute to exceptional outcomes.

A Practice Built on Results

Over the years, I’ve helped thousands of patients feel like themselves again—perhaps better than they’ve felt in decades. From women rediscovering sexual pleasure they thought was lost forever to those finally free from the embarrassment of incontinence, the transformations I witness continuously reaffirm why I’m so passionate about this work.

We track outcomes, follow up diligently with patients, and constantly refine our approaches based on real-world results. Medicine is both science and art, and experience teaches lessons that textbooks can’t convey.

Treating the Whole Person

Beyond the medical expertise, we recognize that you’re a complete person with a full life beyond your symptoms. You might be a mother, a professional, a partner, a friend—juggling numerous responsibilities while dealing with intimate concerns you may feel uncomfortable discussing even with close friends.

We create space for you to be fully heard, fully respected, and fully cared for. Your concerns matter. Your goals matter. You matter.

How Long Do O-Shot Results Last?

One of the most common questions patients ask is about longevity of results. Understanding what to expect helps you plan both financially and practically.

Typical Timeline:

Initial Results (3-6 weeks): Most patients begin noticing improvements within the first month after treatment. This might manifest as increased natural lubrication, enhanced sensation, or improved ease of arousal. Some patients report benefits even sooner, while others take the full six weeks to notice changes.

Peak Results (3-4 months): The full effects of the O-Shot typically develop over several months as tissue regeneration continues. New collagen forms, blood vessels develop, and tissue remodeling progresses. Many patients report that benefits continue increasing even 3-4 months post-treatment.

Duration of Benefits (12-18 months average): Most patients enjoy significant benefits for 12-18 months following a single treatment. However, individual duration varies considerably. Some patients report sustained improvements for two years or longer, while others notice gradual fading of effects around the one-year mark.

Individual Variation

Why such variation? Multiple factors influence how long your results last:

Age and Hormonal Status: Women with optimized hormone levels often enjoy longer-lasting results. Younger women or those on bioidentical hormone replacement therapy frequently report extended benefit duration. Conversely, untreated hormonal deficiency can lead to more rapid fading of results.

Lifestyle Factors: Your daily habits matter. Women who maintain healthy lifestyles—good nutrition, regular exercise, stress management, adequate sleep, no smoking—typically enjoy longer-lasting results. These positive lifestyle factors support ongoing tissue health.

Severity of Initial Concerns: Sometimes more severe tissue changes or functional issues respond well initially but require more frequent maintenance to sustain improvements.

Quality of PRP Used: Higher concentrations of platelets and growth factors may produce longer-lasting effects by stimulating more robust tissue regeneration.

Individual Healing Response: Some people simply heal more robustly than others. This biological variability affects everything from wound healing to response to regenerative treatments.

Maintenance Treatment: Optimizing Long-Term Results

Because the O-Shot effects are progressive but not permanent, most patients benefit from maintenance treatments to sustain their improvements.

Annual Maintenance

Many patients choose to have the O-Shot repeated annually as a proactive maintenance approach. This schedule helps ensure continuous benefit without waiting for effects to fade completely. Think of it like maintaining your car—regular service prevents problems rather than waiting for breakdown.

Assessment-Based Scheduling

Rather than adhering rigidly to a schedule, we prefer monitoring your response and symptoms. When you notice benefits beginning to diminish—perhaps around 12-15 months post-treatment—that’s typically an ideal time to schedule your next treatment. This individualized approach respects your unique response pattern.

Twice-Yearly for Some Patients

Some women, particularly those with more severe initial concerns or ongoing hormonal challenges, find that twice-yearly treatments provide optimal sustained benefit. We’ll discuss what schedule makes sense for your situation based on your initial response.

The Cumulative Effect

An encouraging finding is that some patients report cumulative benefits with repeated treatments. The second or third O-Shot may produce even better results or longer-lasting effects than the first, possibly because tissue quality continues improving with each regenerative stimulus.

Combining with Other Approaches

Maintenance of results often improves when the O-Shot is part of a comprehensive wellness plan. Optimizing hormones, maintaining pelvic floor strength, managing stress, and addressing other health factors all contribute to sustaining sexual wellness long-term.

Beyond the O-Shot: Other Uses for PRP in Greenville

The science behind the O-Shot—using your body’s own growth factors to stimulate healing and regeneration—applies to numerous other conditions and concerns. At Biltmore Restorative Medicine, we use PRP therapy across multiple applications.

Facial Rejuvenation

Often called the “Vampire Facial,” facial PRP has gained popularity for good reason. When applied to facial skin, either through micro-needling or injection, PRP stimulates collagen production, improves skin texture and tone, reduces fine lines and wrinkles, and creates overall facial rejuvenation. The growth factors work just as they do in the O-Shot—signaling tissue to heal and regenerate, but in this case improving facial aesthetics rather than sexual function.

Hair Restoration

Hair loss and thinning can be devastating for both women and men. PRP injections into the scalp can stimulate hair follicles, promote new hair growth, and slow or stop hair loss progression. We’ve seen remarkable results with PRP for androgenetic alopecia (pattern hair loss), particularly when combined with other hair restoration approaches.

Joint and Orthopedic Applications

While perhaps less relevant to our sexual wellness discussion, PRP has shown promise in treating various orthopedic conditions including knee osteoarthritis, tendon injuries, ligament healing, and sports injury recovery. The same regenerative properties that improve sexual function can help repair damaged joints and connective tissue.

Other Aesthetic Applications

PRP can rejuvenate the delicate under-eye area, reducing dark circles and improving skin quality. Neck and décolletage treatments address aging in these often-neglected areas. Hand rejuvenation using PRP can reverse visible signs of aging. Scars, including acne scars, often improve significantly with PRP therapy.

The P-Shot for Men

Just as the O-Shot benefits women’s sexual wellness, the P-Shot (Priapus Shot) uses PRP to address male sexual concerns including erectile dysfunction, decreased sensation, Peyronie’s disease (abnormal penile curvature), and overall sexual performance. At Biltmore Restorative Medicine, we treat men as well as women, recognizing that sexual wellness matters for everyone.

Treating Lichen Sclerosus

This inflammatory skin condition affecting the vulvar area causes itching, pain, and tissue changes that can significantly impact quality of life. While not a cure, PRP treatments have shown promising results for reducing symptoms and improving tissue quality in women with lichen sclerosus.

The versatility of PRP therapy reflects the fundamental nature of what we’re doing—providing concentrated growth factors that stimulate your body’s own healing processes. Whether applied to facial skin, scalp, joints, or intimate tissues, the mechanism remains the same, though the specific protocols and techniques vary by application.

Frequently Asked Questions

Is the O-Shot painful?

This is perhaps the most common concern, and I understand completely—any procedure involving injections in such a sensitive area naturally raises anxiety about discomfort. The good news is that with proper numbing, most patients report minimal to no pain during the procedure.

We apply pharmaceutical-grade numbing cream to the treatment area approximately 20-30 minutes before the injections. This topical anesthetic penetrates the tissue and provides excellent pain relief. By the time we perform the injections, the area is thoroughly numb.

During the actual injection process, most patients report feeling slight pressure but not pain. You might feel a brief sensation of fullness or a minor pinch, but sharp pain is rare when adequate numbing has been achieved. The entire injection portion of the procedure takes only a few minutes.

Some patients experience mild tenderness or soreness after the numbing wears off, similar to how you might feel after any injection. This discomfort is typically minor and easily managed with over-the-counter pain relievers if needed. Most patients find that by the next day, any discomfort has resolved completely.

It’s worth noting that your comfort is our priority. If at any point during the procedure you experience significant discomfort, we can address it. However, this is rarely necessary when proper numbing protocols are followed.

When will I see results from the O-Shot?

The timeline for noticing improvements varies among patients, but understanding the general pattern helps set appropriate expectations.

Early Changes (1-4 weeks): Some patients report improvements within just a few days, though this is less common. More typically, the first noticeable changes occur within 2-4 weeks after treatment. These initial improvements might include increased natural lubrication, slightly enhanced sensation, or beginning improvement in incontinence symptoms.

Progressive Enhancement (1-3 months): As tissue regeneration continues, improvements generally become more pronounced. Between one and three months post-treatment, most patients notice significant enhancement in sexual function, sensitivity, arousal capacity, and orgasmic response. Urinary incontinence continues improving during this period as tissue strengthening progresses.

Peak Results (3-4 months): The full benefits of the O-Shot typically manifest around 3-4 months post-treatment. By this point, new collagen has formed, blood vessel development has progressed, and tissue remodeling is well-established. Many patients report that this is when they feel the most dramatic difference from their pre-treatment baseline.

Continued Improvement: Some patients report that benefits continue enhancing even beyond four months, suggesting that tissue regeneration continues at some level for an extended period.

The gradual timeline reflects the biological reality of what’s happening—we’re stimulating your body’s natural healing and regeneration processes, which take time. Unlike temporary fillers that provide immediate volume, the O-Shot creates lasting change through actual tissue transformation.

During your follow-up appointments, we’ll track your progress and ensure you’re responding as expected. If improvement seems slower than anticipated, we can explore potential factors and discuss whether adjustments to your treatment plan might help.

Can I have sex after getting the O-Shot?

We typically recommend abstaining from sexual activity for 3-4 days following your O-Shot treatment. This brief restriction allows the injection sites to heal properly and helps ensure optimal PRP integration with your tissues.

After this short waiting period, you can resume all normal sexual activity. In fact, some practitioners suggest that sexual activity after the healing period may actually help with results by increasing blood flow to the treated areas, though this hasn’t been formally studied.

You can return to most other normal activities immediately after the procedure. There’s no need to take time off work, avoid exercise (though you might want to skip extremely vigorous activity for a day or two), or significantly alter your routine. The main restriction is simply avoiding penetrative sexual activity and orgasm for those first few days.

This brief waiting period is a small price to pay for the long-term benefits most patients experience. We’ve found that setting clear expectations about this restriction prevents disappointment and helps ensure the best possible outcomes.

Is the O-Shot safe?

The O-Shot is considered very safe, particularly because it uses your own blood-derived PRP. When you use your own tissue as the therapeutic agent, risks of allergic reaction or rejection are essentially eliminated—your body doesn’t react negatively to its own materials.

Safety Track Record

Since Dr. Runels developed the O-Shot, thousands of procedures have been performed worldwide with an excellent safety record. Serious complications are extremely rare when the procedure is performed by properly trained providers using correct technique.

FDA Status

It’s important to understand that PRP procedures, including the O-Shot, exist in a regulatory gray area. The FDA regulates the devices used to process PRP, but the procedure itself is not FDA-approved in the way pharmaceutical drugs are. This doesn’t indicate lack of safety—rather, it reflects how the FDA categorizes procedures using a patient’s own tissue.

Many common medical procedures fall into this same category, where the technique is considered part of medical practice rather than requiring specific FDA approval. We use FDA-cleared centrifuge systems and follow established protocols to ensure both safety and efficacy.

Minimizing Risks

At Biltmore Restorative Medicine, we minimize potential risks through:

  • Rigorous sterile technique
  • Use of quality, FDA-cleared equipment
  • Thorough patient evaluation before treatment
  • Clear communication about post-procedure care
  • Availability for follow-up if any concerns arise

When to Seek Medical Attention

While complications are rare, you should contact us immediately if you experience:

  • Signs of infection (increasing pain, redness, warmth, fever, unusual discharge)
  • Unexpected bleeding
  • Severe pain not relieved by over-the-counter medications
  • Any symptom that concerns you

The safety profile of the O-Shot is one of its significant advantages over more invasive surgical approaches to sexual dysfunction or incontinence.

What if the O-Shot doesn’t work for me?

While the majority of patients experience significant benefits from the O-Shot, individual responses vary. Not everyone achieves the degree of improvement they hoped for, and it’s important to have a plan if this happens.

Understanding Non-Response

Several factors might contribute to limited response:

  • Inadequate hormone levels, particularly estrogen, may limit tissue’s ability to respond to PRP stimulation
  • Severe tissue damage or changes might require multiple treatments to achieve noticeable improvement
  • Certain health conditions or medications can affect healing capacity
  • The quality or concentration of PRP used makes a substantial difference
  • Sometimes the underlying cause of dysfunction is more complex than PRP alone can address

Our Approach

If your response to the initial treatment is less than we hoped, we don’t simply give up. Instead, we explore why and what we might do differently:

Hormone Optimization: Often, optimizing hormone levels—particularly estrogen and testosterone—dramatically improves response to subsequent PRP treatments. If we haven’t already addressed your hormone status, this becomes our first priority.

Combination Approaches: Sometimes combining the O-Shot with other treatments produces better results. This might include pelvic floor physical therapy, vaginal laser treatments, or other complementary approaches.

Repeat Treatment: Some patients respond better to a second or third treatment, possibly because each successive treatment builds on the tissue improvements from the previous one.

Alternative Options: If the O-Shot simply doesn’t seem to be the right fit for your situation, we discuss alternatives. These might include hormone therapy, other regenerative approaches, or referral to specialists in pelvic floor disorders or sexual medicine if appropriate.

Our Commitment

At Biltmore Restorative Medicine, we’re invested in your outcomes. If you don’t achieve the results we both hoped for, we work with you to understand why and explore alternatives. You’re not just a transaction—you’re a patient we’re committed to helping feel like yourself again.

Can I get the O-Shot if I’m pregnant or breastfeeding?

We typically do not recommend the O-Shot during pregnancy or while actively breastfeeding, though for somewhat different reasons in each case.

During Pregnancy

While PRP itself is not harmful (it’s your own blood), we avoid elective procedures during pregnancy as a general principle. Pregnancy also causes significant hormonal changes and physical changes to pelvic tissues that make it difficult to assess what improvements might come from treatment versus normal postpartum healing.

Additionally, many of the concerns that prompt women to seek the O-Shot—such as urinary incontinence or changes in sexual function—often improve naturally in the months following delivery as tissues heal and hormones normalize.

While Breastfeeding

The concerns here are less about safety and more about timing. Breastfeeding involves unique hormonal states that can affect vaginal tissue and sexual function. Many breastfeeding women experience vaginal dryness due to lower estrogen levels—a temporary situation that resolves when nursing ends or decreases.

Treating while in this temporary hormonal state might not provide lasting benefit, since the underlying hormonal environment changes once breastfeeding concludes. We typically prefer to wait until you’ve stopped nursing or significantly reduced nursing frequency before performing the O-Shot.

Optimal Timing

For postpartum women, we generally recommend waiting until:

  • At least 6-8 weeks after delivery (to allow initial healing)
  • Breastfeeding has concluded or significantly decreased
  • Your menstrual cycle has returned (indicating more normal hormonal function)
  • You’ve had time to assess which symptoms persist after the initial postpartum period

This timing allows us to address true persistent issues rather than temporary symptoms that might resolve on their own. It also ensures the O-Shot is performed in a hormonal environment where it can provide lasting benefit.

Of course, individual situations vary. During your consultation, we’ll discuss your specific circumstances and help you determine the optimal timing for treatment.

How does the O-Shot compare to other treatments?

Women seeking solutions for sexual dysfunction, vaginal dryness, or urinary incontinence have several options. Understanding how the O-Shot compares to alternatives helps you make an informed decision.

Hormone Therapy Comparison:

Hormone replacement therapy, particularly estrogen therapy, effectively addresses many symptoms of menopause including vaginal dryness and tissue changes. Local vaginal estrogen (cream, tablet, or ring) specifically targets vaginal and urinary symptoms with minimal systemic absorption.

Advantages of Hormone Therapy: Addresses multiple symptoms simultaneously, including hot flashes and night sweats. May provide protective effects against osteoporosis and cardiovascular disease. Often covered by insurance.

Advantages of the O-Shot: Non-hormonal option for women who can’t or don’t want to use hormones. Can enhance sexual function in ways hormones alone might not. Works well in combination with hormone therapy for synergistic effects.

At Biltmore Restorative Medicine, we often recommend combining optimized hormone therapy with the O-Shot, as the two approaches complement each other beautifully. Proper estrogen levels ensure tissues can respond optimally to the regenerative signals from PRP.

Surgical Options Comparison:

Surgical treatments for stress urinary incontinence (like sling procedures) or vaginal prolapse repair address structural issues through surgical intervention.

Advantages of Surgery: May provide more dramatic improvement for severe structural issues. Often covered by insurance for incontinence. Results can be very long-lasting.

Advantages of the O-Shot: Non-surgical, no incisions, no general anesthesia required. Minimal recovery time. Lower risk profile. Can be repeated easily. Doesn’t preclude surgery later if needed.

For many women with mild to moderate stress incontinence, the O-Shot provides significant improvement without surgical risks and recovery.

Laser Treatments Comparison:

Vaginal laser treatments (like MonaLisa Touch or FemiLift) use fractional CO2 or erbium lasers to stimulate collagen production in vaginal tissue.

Advantages of Laser Treatments: No injections, typically comfortable procedures. Often effective for vaginal dryness and mild laxity. Can be combined with the O-Shot.

Advantages of the O-Shot: Uses your own growth factors rather than thermal energy. May provide more dramatic enhancement of sexual sensation and function. Single treatment often sufficient vs. multiple laser sessions typically needed.

Some practitioners combine laser treatments with the O-Shot for synergistic effects.

Medications for Sexual Dysfunction:

Options like Addyi (flibanserin) or Vyleesi (bremelanotide) specifically target female sexual dysfunction through hormonal or neurological pathways.

Advantages of Medications: Covered by some insurance plans. Don’t require procedures. Can be discontinued if side effects occur.

Advantages of the O-Shot: Single treatment provides long-lasting benefits vs. daily medication. No systemic side effects. Addresses multiple concerns simultaneously. Often more effective based on patient reports.

The Bottom Line

For many women, the O-Shot offers an ideal balance of safety, efficacy, and minimal disruption to life. It’s particularly attractive for women seeking:

  • A non-hormonal option
  • Treatment for multiple concerns simultaneously
  • Minimal recovery time
  • Long-lasting but not permanent effects (since you can assess ongoing need)
  • Lower risk than surgical intervention

Will my insurance cover the O-Shot?

The O-Shot is considered an elective procedure and is not covered by standard health insurance plans. This includes Medicare and Medicaid as well as private insurance. There are several reasons for this classification:

Elective Nature: Insurance typically covers treatments deemed medically necessary to treat disease or prevent serious health consequences. While the O-Shot addresses quality-of-life concerns, it’s not considered medically necessary in the traditional insurance sense.

Lack of FDA Approval: Because PRP procedures like the O-Shot haven’t gone through the formal FDA approval process required for pharmaceutical drugs or devices, insurance companies don’t cover them.

Alternative Treatments Available: For concerns like urinary incontinence, insurance-covered options exist (like pelvic floor physical therapy or surgical procedures). Insurance companies point to these covered alternatives when declining coverage for the O-Shot.

HSA and FSA Funds

While insurance won’t cover the procedure, you may be able to use funds from your Health Savings Account (HSA) or Flexible Spending Account (FSA) to pay for the O-Shot. These pre-tax accounts can often be used for a wide range of medical expenses including many elective procedures.

Check with your HSA or FSA administrator to confirm eligibility, as policies vary. Generally, if a procedure is performed by a licensed medical professional to treat a medical condition or symptom, HSA/FSA funds can be used.

Tax Deductions

In some cases, medical expenses including elective procedures can be tax-deductible if they exceed a certain percentage of your adjusted gross income. Consult with a tax professional about your specific situation.

Financing Options

Because we recognize that the out-of-pocket cost represents a significant investment, many practices including ours work with medical financing companies that offer payment plans. These plans allow you to spread the cost over several months, making the procedure more accessible.

While the lack of insurance coverage is disappointing, many patients find the investment worthwhile given the dramatic improvements in quality of life and the long-lasting nature of results.

Can the O-Shot help with menopause symptoms?

Menopause brings numerous changes, many of which directly affect sexual function and urinary health. The O-Shot can effectively address several menopause-related concerns.

Vaginal Dryness: Perhaps the most common menopausal symptom affecting sexual function, vaginal dryness occurs as declining estrogen levels reduce natural lubrication. The O-Shot stimulates regeneration of vaginal tissue, including the glands that produce natural moisture. Many patients report significant improvement in natural lubrication, making intercourse comfortable again without artificial lubricants.

Tissue Thinning and Fragility: As estrogen levels decline, vaginal tissue becomes thinner, less elastic, and more fragile—a condition called vaginal atrophy or genitourinary syndrome of menopause. This can cause discomfort during intercourse and increase susceptibility to irritation and infection. The O-Shot promotes tissue regeneration and collagen production, effectively reversing some of these changes and creating healthier, more resilient tissue.

Loss of Sensation: Many postmenopausal women notice decreased sensation during intimacy. The nerve endings become less sensitive, and decreased blood flow reduces arousal capacity. By improving tissue health and blood vessel formation, the O-Shot often restores sensitivity and makes pleasure more accessible.

Urinary Symptoms: Stress urinary incontinence commonly worsens after menopause as tissue supporting the urethra weakens. The strengthening effects of the O-Shot frequently provide significant relief from these embarrassing symptoms.

Loss of Libido: While the O-Shot doesn’t directly address hormonal causes of low libido, many women find that when sex becomes more pleasurable and comfortable, interest naturally increases. Addressing the physical barriers to enjoyment often rekindled desire.

Integration with Hormone Therapy

At Biltmore Restorative Medicine, we often recommend combining the O-Shot with hormone optimization therapy for menopausal women. This combination approach addresses menopause on multiple levels:

  • Systemic hormone therapy (bioidentical estrogen, progesterone, testosterone) addresses hot flashes, mood changes, energy levels, bone density, cardiovascular health, and provides some improvement in vaginal symptoms
  • The O-Shot provides targeted regenerative treatment specifically for sexual function and urinary health
  • Together, they create synergistic effects that exceed what either treatment achieves alone

Proper estrogen levels also enhance your tissue’s ability to respond to the regenerative signals from PRP, potentially improving outcomes from the O-Shot itself.

Beyond Sexual Health

As someone who regularly speaks on the dangers of untreated menopause and advocates for hormone optimization, I want to emphasize that addressing menopausal symptoms isn’t just about quality of life—though that matters enormously. Proper hormone optimization is the most natural and safest way to lower risks of cardiac disease, Alzheimer’s, osteoporosis, and many other ailments associated with estrogen deficiency.

The O-Shot represents one tool in a comprehensive approach to healthy aging for women. It’s not a replacement for hormone therapy but rather a complement that can enhance your overall wellness and vitality.

Is there an age limit for getting the O-Shot?

There’s no strict age limit for the O-Shot, either upper or lower. Instead, candidacy depends on your specific situation, concerns, and overall health rather than your age per se.

Younger Women

Women in their 20s, 30s, and 40s can certainly benefit from the O-Shot if they’re experiencing sexual dysfunction, difficulty achieving orgasm, or other concerns the treatment addresses. Younger women often respond very robustly to PRP therapy because their tissues typically have excellent regenerative capacity.

Some younger women have always struggled with sexual function issues. Others develop concerns after childbirth or due to medical conditions. The O-Shot can be life-changing for these women, who may have assumed they’d struggle with these issues indefinitely.

Perimenopausal Women

Women in their 40s and early 50s going through perimenopause often notice changes in sexual function before their periods stop completely. This can be an ideal time for the O-Shot, as addressing these changes early may prevent more significant issues from developing.

Postmenopausal Women

Women in their 50s, 60s, 70s, and beyond can achieve excellent results from the O-Shot. While regenerative capacity may diminish somewhat with age, particularly in the context of lower estrogen levels, postmenopausal women still respond very positively to PRP therapy.

I’ve treated women well into their 70s and 80s who have experienced dramatic improvements in sexual function, urinary continence, and quality of life. The desire for intimacy and pleasure doesn’t disappear with age, and neither does the right to address concerns affecting these aspects of life.

Factors More Important Than Age

Rather than age, we consider:

  • Your overall health status
  • Hormonal levels (optimizing these often improves outcomes)
  • Specific concerns you’re seeking to address
  • Realistic expectations
  • Any medical conditions that might affect healing
  • Your goals for treatment

Optimizing Outcomes at Any Age

Regardless of your age, certain factors help optimize your response to the O-Shot:

  • Addressing hormonal imbalances, particularly in older women
  • Maintaining overall good health
  • Not smoking
  • Managing chronic conditions like diabetes
  • Having realistic expectations based on your starting point

During your consultation, we’ll assess your individual situation and discuss what outcomes you can realistically expect given your age, health status, and specific concerns. Age is just one factor in a complex equation, not a determining limitation.

Making Your Decision: Taking the Next Step

If you’re considering the O-Shot, you’ve already taken the most important step—acknowledging that your sexual wellness matters and deserves attention. Too many women suffer silently with concerns that significantly affect their quality of life, assuming nothing can be done or feeling too embarrassed to seek help.

Preparing for Your Consultation

When you’re ready to schedule a consultation, preparing beforehand helps ensure you get the most from your visit:

Write Down Your Questions

Don’t rely on memory during your appointment. Write down everything you want to know, from specific questions about the procedure to concerns about recovery or costs. No question is too minor or too personal.

List Your Symptoms

Be specific about what you’re experiencing:

  • How long have you had these concerns?
  • How do they affect your daily life?
  • What makes them better or worse?
  • What have you tried already?
  • How significantly do they impact your relationships or self-confidence?

Gather Your Medical History

Bring a list of:

  • Current medications and supplements
  • Past surgeries or procedures
  • Chronic health conditions
  • Hormone levels if you’ve had recent testing
  • Relevant gynecological history

Consider Your Goals

Think about what improvement would mean to you. What would success look like? What aspects of your sexual wellness are most important to address?

Evaluating Your Comfort Level

The technical aspects of provider qualification matter, but so does something less tangible—your comfort level. Sexual wellness requires vulnerability, and you deserve to work with a provider who makes you feel:

Heard and Respected: Do they listen carefully to your concerns? Do they take your symptoms seriously? Do they respect your knowledge of your own body and your right to make informed decisions?

Safe and Comfortable: Can you discuss intimate topics without embarrassment? Does the environment feel professional yet warm? Do you feel rushed, or does the provider give you adequate time?

Confident in Their Expertise: Do they answer your questions thoroughly and honestly? Do they explain things clearly? Do they acknowledge limitations or areas of uncertainty rather than promising unrealistic results?

Aligned in Approach: Do their treatment philosophy and style match what you’re looking for? If you want a comprehensive, whole-person approach, does the provider offer that? If you prefer straightforward, procedure-focused care, does their style align?

Trust your instincts. If something doesn’t feel right—even if you can’t articulate exactly what—it’s okay to seek care elsewhere. The right provider-patient relationship matters enormously in achieving good outcomes.

Reading Reviews and Testimonials

Patient reviews offer valuable insights, but read them thoughtfully:

Look for Patterns: One negative review might be an outlier, but multiple patients reporting similar concerns should raise red flags. Similarly, consistent positive feedback about specific aspects of care (like thoroughness of consultation or attentiveness to comfort) tells you something meaningful.

Consider the Source: Reviews on the provider’s own website may be curated. Check independent review platforms like Google, Healthgrades, or Yelp for more balanced perspectives.

Read Between the Lines: Look for reviews that mention specific experiences rather than generic praise or criticism. Detailed reviews tend to be more reliable.

Remember Individual Variation: Someone else’s experience won’t be exactly yours. Results vary, and what worked wonderfully for one patient might work differently for you based on your unique circumstances.

Don’t Expect Perfection: No provider has exclusively five-star reviews. What matters more is how they respond to concerns and whether negative reviews raise consistent red flags about important issues.

Making an Informed Choice

With your research complete, consultations scheduled, and questions answered, you’re ready to make a decision. Consider:

Comparing Providers

If you’ve consulted with multiple providers, compare them across key dimensions:

  • Training, certification, and experience
  • Quality of PRP processing and concentration achieved
  • Comprehensiveness of approach
  • Your comfort level and confidence in each provider
  • Cost and value (not just the lowest price, but the best value)
  • Convenience of location and scheduling

Weighing Cost Versus Quality

While cost matters, the cheapest option isn’t always the best value. Consider what you’re receiving for your investment. Higher costs may reflect:

  • Superior PRP quality and concentration
  • More experienced providers
  • More comprehensive care and follow-up
  • Better facilities and equipment
  • Longer consultation and procedure times

Trusting Your Research

You’ve done the work to educate yourself. Trust the knowledge you’ve gained and the conclusions you’ve reached. If a provider checks all the boxes and feels right, move forward with confidence.

Scheduling Your Treatment

Once you’ve selected your provider, schedule your procedure for a time that’s convenient and allows you to follow post-procedure guidelines. Avoid scheduling immediately before important events where you need to abstain from sexual activity.

Conclusion: Your Path to Renewed Wellness

Sexual wellness profoundly affects quality of life, relationships, self-confidence, and overall happiness. The concerns that prompted you to research the O-Shot—whether diminished pleasure, uncomfortable dryness, embarrassing incontinence, or other issues—aren’t minor inconveniences. They’re legitimate medical concerns that deserve effective treatment.

The O-Shot represents a breakthrough in addressing these concerns through regenerative medicine—harnessing your body’s own healing mechanisms to restore function, sensation, and pleasure. While not appropriate for everyone and not guaranteed to resolve every symptom, it has helped thousands of women feel like themselves again—perhaps better than they’ve felt in years or even decades.

Finding the right provider makes all the difference in your experience and outcomes. The expertise, technique, PRP quality, and comprehensive approach vary significantly among providers. Taking time to thoroughly vet potential providers, ask detailed questions, and choose someone qualified and experienced will serve you well.

At Biltmore Restorative Medicine & Aesthetics, we’ve built our practice on a foundation of exceptional training, uncompromising quality, and genuine commitment to helping patients achieve their wellness goals. Our whole-person approach recognizes that sexual wellness connects to hormone balance, overall health, and numerous other factors. We don’t just perform procedures—we partner with you in your journey toward optimal health and vitality.

Whether you’re dealing with changes from aging, menopause, childbirth, or other factors affecting your sexual wellness, solutions exist. The O-Shot may be part of your answer. Combined with hormone optimization and other approaches when appropriate, it can help you feel like YOU again.

Ready to Take the Next Step?

If you’re in the Greenville area and want to explore whether the O-Shot is right for you, we invite you to schedule a private consultation. We’ll take time to understand your concerns, evaluate your individual situation, discuss realistic expectations, and create a personalized plan to help you achieve your wellness goals.

Visit us at biltmorerestorativemedicine.com or oshotgreenville.com to learn more and schedule your consultation.

We can’t wait to help you feel like YOU again!